Table 3. Criteria for borderline resectable pancreatic cancer.
Vessel | MD Anderson [2006] | AHPBA/SSAT/SSO [2008] | Alliance A021101 Trial [2013] | IAP [2016] | NCCN 1.2019 [2018] |
---|---|---|---|---|---|
SMV-PV | Short-segment occlusion with suitable vessel above and below; segmental venous occlusion alone without SMA involvement is rare and should be apparent on CT images | Abutment >180° or occlusion amenable to resection and reconstruction | Interface between tumor and vessel measuring ≥180° and/or reconstructable occlusion | Tumor contact ≥180° or invasion of the SMV/PV with bilateral narrowing or occlusion, and not exceeding the inferior border of the duodenum | Solid tumor contact with the SMV or PV of >180°, contact of ≤180° with contour irregularity of the vein or thrombosis of the vein but with suitable vessel proximal and distal to the site of involvement allowing for resection and vein reconstruction |
SMA | Tumor abutment ≤180°; periarterial stranding and tumor points of contact forming a convexity against the vessel improve chances of resection | Abutment <180° | Interface between tumor and vessel <180° of vessel | Tumor contact/invasion of ≤180° without showing stenosis/deformity | Solid tumor contact with the SMA of ≤180° |
CHA | Short-segment encasement/abutment of the common hepatic artery (typically at the GDA origin); the surgeon should be prepared for vascular resection/ interposition grafting | Abutment or short-segment encasement, amenable to reconstruction | Reconstructable, short-segment interface between tumor and vessel of any degree | Tumor contact/invasion without showing tumor contact/invasion of the PHA and/or CA | Solid tumor contact with CHA without extension to CA or HA bifurcation allowing for complete resection and reconstruction |
Celiac axis | Abutment of ≤180° of the circumference of the celiac axis | No abutment or encasement | Interface between tumor and vessel <180° of vessel | Tumor contact/invasion of ≤180° without showing stenosis/deformity | Solid tumor contact with the CA of ≤180° or of >180° without involvement of the aorta and with intact and uninvolved GDA thereby permitting a modified Appleby procedure |