Table 1.
Baseline characteristics, presentation signs and symptoms and laboratory results.a
| COVID-19 Diagnosis |
||||
|---|---|---|---|---|
| Total patients (n = 159), No. (%) | Yes (n = 86), No. (%) |
No (n = 73), No. (%) |
P-value | |
| Demographic Information | ||||
| Age, mean (SD), y | 57.9 (18.0) | 60.0 (15.2) | 55.4 (20.6) | .12 |
| Male | 88 (55.3) | 53 (61.6) | 35 (47.9) | .10 |
| Comorbidities | 103 (64.8) | 58 (67.4) | 45 (61.6) | .40 |
| Cancer | 11 (6.9) | 6 (7) | 5 (6.8) | >.99 |
| Hypertension | 52 (32.7) | 31 (36) | 21 (28.8) | .31 |
| Coronary artery disease | 8 (5) | 3 (3.5) | 5 (6.8) | .57 |
| Congestive heart failure | 3 (1.9) | 0 (0) | 3 (4.1) | .19 |
| Diabetes | 20 (12.6) | 13 (15.1) | 7 (9.6) | .38 |
| Hematologic disease | 2 (1.3) | 1 (1.2) | 1 (1.4) | >.99 |
| Immunosuppression | 8 (5) | 3 (3.5) | 5 (6.8) | .57 |
| Liver disease | 2 (1.3) | 2 (2.3) | 0 (0) | .54 |
| Obesity (BMI ≥ 30) | 97 (61.0) | 56 (65.1) | 41 (56.2) | .64 |
| Pulmonary disease | 33 (20.8) | 14 (16.3) | 19 (26.0) | .21 |
| Smoker | 7 (4.4) | 2 (2.3) | 5 (6.8) | .33 |
| Signs and symptoms | ||||
| Anosmia | 9 (5.7) | 9 (10.5) | 0 (0) | .01 |
| Chest pain | 19 (11.9) | 5 (5.8) | 14 (19.2) | .02 |
| Cough | 114 (71.7) | 67 (77.9) | 47 (64.4) | .06 |
| Diarrhea | 1 (0.6) | 1 (1.2) | 0 (0) | .57 |
| Dyspnea | 86 (54.1) | 49 (57.0) | 37 (50.7) | .42 |
| Fatigue | 82 (51.6) | 29 (57.0) | 33 (45.2) | .15 |
| Headache | 41 (25.8) | 19 (22.1) | 22 (30.1) | .35 |
| Myalgia | 55 (34.6) | 35 (40.7) | 20 (27.4) | .09 |
| Rhinorrhea | 36 (22.6) | 18 (20.9) | 18 (24.7) | .74 |
| Temperature ≥ 37.8 °C | 35 (22.0) | 23 (26.7) | 12 (16.4) | .14 |
| Oxygen saturation ≤93% | 31 (19.5) | 23 (26.7) | 8 (11.0) | .006 |
| Initial laboratory measures | ||||
| Leukocytes, median (IQR), /mm3 | 6820 (4915−9540) | 5930 (4460−7510) | 9230 (6760−11480) | .001 |
| Lymphocyte, median (IQR), /mm3 | 1290 (880−1785) | 1165 (850−1510) | 1610 (970−2150) | .005 |
| Platelets, median (IQR), /mm3 | 188.000 (253.000−144.500) | 166.000 (130.000−204.000) | 218.000 (179.000−273.000) | .001 |
| C-reactive protein, median (IQR), mg/dL | 3.75 (1.10−7.30) | 4.00 (1.80−7.30) | 3.50 (0.60−7.30) | .22 |
| Creatinine, mg/dL, median (IQR), mg/dL | 0.90 (0.70−1.10) | 0.90 (0.70−1.10) | 0.90 (0.70−1.05) | .86 |
| d-dimer, median (IQR), ng/mL | 512.0 (349.0−795.0) | 512.0 (286.5−773.0) | 479.0 (336.0−1256.0) | .96 |
Abbreviations: COVID-19, coronavirus disease 2019; SD, standard deviation; BMI, body mass index; IQR, interquartile range.
Please note, subtitles rows do not have data.
a
Presentation symptoms, vital signs, and laboratory results were selected to be included according to the relevance to the characterization of patients with COVID-19.