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Cartoon representation of the HCoV-OC43 spike protein (PDB code:6NZK) S1Adomain binding to O-sialic acid. The side chains of residues within 4.5 Å from sialic acid (N27, K29, T31, L80, K81, G82, S83, L85, L86, S87, W90) are indicated. The residues that form hydrogen bonds with sialic acid are shown in bold and italics.
