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. 2020 Oct 31;102:233–238. doi: 10.1016/j.ijid.2020.10.067

Table 3.

Factors associated with poor clinical outcome during follow-up (death/transfer to ICUa) among patients without dyspnea – Multivariable logistic regressions (n = 1,107).

Model A Model B Model C Model D
OR 95%CIc OR 95%CIc OR 95%CIc OR 95%CIc
Sex (ref. Men)
 Women 1.40[0.54;3.63] 1.67[0.62;4.47] 1.44[0.55;3.80] 1.65[0.61;4.46]



Age (ref. 18−64)
 >64 1.14[0.35;3.69] 1.11[0.36;3.43] 1.19[0.37;3.86] 1.10[0.35;3.42]



Risk factors
 Diabetes mellitus 0.99[0.34;2.85] 0.72[0.23;2.23] 0.88[0.30;2.63] 0.72[0.23;2.25]
 Hypertension 1.90[0.64;5.63] 1.79[0.60;5.32] 1.74[0.57;5.28] 1.65[0.54;5.00]
 Cancer 1.21[0.33;4.47] 1.44[0.40;5.21] 1.05[0.29;3.90] 1.30[0.36;4.72]
 Chronic heart diseases 3.92[1.34;11.50] 4.27[1.44;12.66] 3.83[1.28;11.43] 4.15[1.37;12.52]
 Chronic respiratory disease 0.66[0.16;2.65] 1.15[0.28;4.70] 0.70[0.17;2.85] 1.02[0.25;4.20]
 Obesity 1.27[0.39;4.16] 0.91[0.27;3.12] 1.11[0.33;3.75] 0.86[0.24;3.00]



Time from symptom onset to admission (ref. < 3days (or no symptom))
 Between 3 and 5 days 1.66[0.46;5.96] 1.68[0.43;6.47] 1.44[0.40;5.26] 1.49[0.39;5.72]
 >5 days 1.46[0.45;4.74] 0.82[0.23;2.92] 1.32[0.40;4.29] 0.74[0.21;2.66]



NEWS score (ref. 0−4)
 NEWS >4 15.40[4.99;47.49] 9.64[3.18;29.21] 9.02[2.72;29.96] 6.82[2.13;21.87]



LDCT scanner severity score (ref. normal/limited)
 Medium-severe 9.45[3.02;29.62] 7.88[2.48;25.00]
O2 Sat (min = 63–max = 100) 0.78[0.65;0.93] 0.82[0.67;1.00]
AIC/c- statistic 187 / 0.93 172 / 0.93 182 / 0.94 170 / 0.94
(Area Under ROC Curve)

a23/1107 (2.1%) of patients were transferred to an ICU/and or died during follow-up.

bList of included risk factors: hypertension, obesity, cancer, diabetes, cardiac disease, and chronic respiratory disease (see Table 1).

c

Adjusted odds ratio with 95% confidence interval.