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. 2020 Oct 28;12:10669–10678. doi: 10.2147/CMAR.S266421

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© 2020 Liu et al.

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Downregulation of miR-15b-5b inhibits the proliferation of prostate PC-3 cells. (A) qRT-PCR was performed to detect the expression of miR-15b-5b following miR-15b-5b suppressing. (B) Cell Counting Kit-8 (CCK-8) assay was used to assess the proliferation of PC-3 cells with or without miR-15b-5b suppression. (C) The colony-forming capacity of prostate cancer PC-3 cells was detected by colony formation assay (Magnification:1×). (D) The number of the colonies was decreased following miR-15b-5b suppression compared with the control. Comparisons were performed using the paired t-test. **Indicates p <0.01. Error bars represent SEM. Data represent three independent experiments.