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. 2020 Oct 28;12:10669–10678. doi: 10.2147/CMAR.S266421

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© 2020 Liu et al.

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LATS2 expression is down-regulated by miR-15b-5p during prostate cancer development. (A) Western blot was performed to detect LATS2 protein expression in prostate cancer tissues. (B) LATS2 was down-regulated in prostate cancer PC-3 cells. (C) MiR-15b-5b restricted the expression of LATS2. (D) The expression of LATS2 was up-regulated following inhibition of miR-15b-15b. Comparisons were performed using the paired t-test. *Indicates p <0.05, **Indicates p <0.01. Error bars represent SEM. Data represent three independent experiments.