TABLE 2.
Description of the differentially expressed transcription factors (TFs) detected in the present study.
| Gene symbol | Description† | Expression |
| Atf3* | Activating transcription factor 3 | Upregulated |
| Batf2* | Basic leucine zipper transcription factor, ATF-like 2 | Upregulated |
| Bcl3* | B cell leukemia/lymphoma 3 | Upregulated |
| Eif2ak2* | Eukaryotic translation initiation factor 2-alpha kinase 2 | Upregulated |
| Ikzf1* | IKAROS family zinc finger 1 | Upregulated |
| Irf1* | Interferon regulatory factor 1 | Upregulated |
| Irf8* | Interferon regulatory factor 8 | Upregulated |
| Irf9* | Interferon regulatory factor 9 | Upregulated |
| Spi1* | Spleen focus forming virus (SFFV) proviral integration oncogene | Upregulated |
| Stat1* | Signal transducer and activator of transcription 1 | Upregulated |
| Stat2* | Signal transducer and activator of transcription 2 | Upregulated |
| Batf3# | Basic leucine zipper transcription factor, ATF-like 3 | Upregulated |
| Cd7# | CD7 antigen | Upregulated |
| Csf1# | Colony stimulating factor 1 (macrophage) | Upregulated |
| Elf1# | E74-like factor 1 | Upregulated |
| Elk3# | ELK3, member of ETS oncogene family | Upregulated |
| Ets1# | E26 avian leukemia oncogene 1, 5′ domain | Upregulated |
| Fli1# | Friend leukemia integration 1 | Upregulated |
| Gfi1# | Growth factor independent 1 transcription repressor | Upregulated |
| Hlx# | H2.0-like homeobox | Upregulated |
| Irf4# | Interferon regulatory factor 4 | Upregulated |
| Irf5# | Interferon regulatory factor 5 | Upregulated |
| Mcm6# | Minichromosome maintenance complex component 6 | Upregulated |
| Nfkb1# | Nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 | Upregulated |
| Pax6# | Paired box 6 | Upregulated |
| Pou2af1# | POU domain, class 2, associating factor 1 | Upregulated |
| Prdm1# | PR domain containing 1, with ZNF domain | Upregulated |
| Runx1# | Runt related transcription factor 1 | Upregulated |
| Runx3# | Runt related transcription factor 3 | Upregulated |
| Spib# | Spi-B transcription factor (Spi-1/PU.1 related) | Upregulated |
| Stat3# | Signal transducer and activator of transcription 3 | Upregulated |
| Tcf3# | Transcription factor 3 | Upregulated |
| Etv1# | Ets variant 1 | Downregulated |
| Fos# | FBJ osteosarcoma oncogene | Downregulated |
| Gtf2i# | General transcription factor II I | Downregulated |
| Pias3# | Protein inhibitor of activated STAT 3 | Downregulated |
| Tfap2a# | Transcription factor AP-2, alpha | Downregulated |
| Trps1# | Transcriptional repressor GATA binding 1 | Downregulated |
*Shared differentially expressed TFs between acutely and chronically infected mice. #Differentially expressed TFs in chronically infected mice only. †Functional descriptions of TFs were retrieved from mouse transcriptome dataset (GRCm38.p6; Ensembl database Release-100).