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. 2020 Oct 19;8:558961. doi: 10.3389/fcell.2020.558961

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Copyright © 2020 Du, Yan, Mi, Li, Ji, Hou, Ma, Ba, Zhou, Chen, Xie and Hu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Associations of the stemness index with the immune microenvironment in GBM. (A–D) Correlation between mRNAsi and ESTIMATE score (A), stromal score (B), immune score (C), the relative expression of PD-L1 (D). (E–F) Differences in immune-related cellular pathways (E) and nine oncogenic pathways (F) between low and high mRNAsi groups in the TCGA-GBM cohort. The upper and lower ends of the boxes represented an interquartile range of values. The lines in the boxes represented the median value, and the dots showed outliers. The asterisks represented the statistical P-value *P < 0.05; **P < 0.01; ***P < 0.001, ns, no significant.