Table 2.
Differences in Laboratory findings in patients with severe COVID-19.
| Variables | All patients (n = 45) | Intubated (n = 20) | Not intubated (n = 25) | P |
|---|---|---|---|---|
| Pao2/Fio2 ratio (mm Hg) | 170.0 (115.5–218.2) | 130.6 (100.2–197.0) | 198.8 (142.4–279.1) | 0.0030 |
| Paco2 (mm Hg) | 38.3 (35.5–41.5) | 40.3 (34.5–47.6) | 38.0 (35.1–39.7) | 0.1142 |
| White blood cell count ( ×109/L) | 8.3 (5.6–10.3) | 9.7 (7.4–12.9) | 6.5 (4.8–9.2) | 0.0037 |
| Neutrophil count ( ×109/L) | 6.8 (4.4–9.5) | 9.0 (6.330–13.15) | 5.5 (3.8–8.3) | 0.0022 |
| Lymphocyte count ( ×109/L) | 0.5 (0.3–0.7) | 0.4 (0.3–0.5) | 0.7 (0.5–0.9) | <0.001 |
| Hemoglobin (g/L) | 121.0 (111.0–133.0) | 115.5 (105.5–122.5) | 129.0 (116.5–141.0) | 0.0024 |
| Platelet count ( ×109/L) | 189.7 ± 72.7 | 165.5 ± 51.5 | 209.0 ± 81.9 | 0.0448 |
| Prothrombin time (s) | 13.4 (12.3–14.9) | 14.6 (13.2–15.2) | 13.1 (12.0–13.7) | 0.0341 |
| Activated partial thromboplastin time (s) | 35.8 (28.4, 41.4) (n = 37) | 38.9 (35.1, 46.9) (n = 18) | 32.1 (26.0,36.0) (n = 19) | 0.0880 |
| Fibrinogen (g/L) | 4.61 (3.61, 5.62) (n = 37) | 4.92 (3.67, 6.12) (n = 18) | 4.59 (3.8, 5.1) (n = 19) | 0.1510 |
| d-Dimer (ng/mL) | 980 (556, 1,807) (n = 35) | 1,490 (859, 2,297) (n = 18) | 741 (4,480, 1,231) (n = 17) | 0.0235 |
| Troponin I (μg/L) | 0.01 (0.01–0.02) (n = 40) | 0.03 (0.02–0.05) (n = 20) | 0.01 (0.00–0.01) (n = 20) | <0.001 |
| Lactate dehydrogenase (U/L) | 338.0 (248.0–437.9) | 397.1 (342.2–523.8) | 285.3 (215.5–346.7) | 0.0012 |
| Creatine kinase (U/L) | 66.5 (44.7–114.4) (n = 43) | 83.0 (52.2–221.2) (n = 20) | 45.0 (30.6–75.4) (n = 23) | 0.0034 |
| Serum creatinine (μmol/L) | 67.6 (54.2–86.0) (n = 44) | 75.6 (61.8–116.0) (n = 20) | 62.7 (53.3–78.9) (n = 24) | 0.0305 |
| Total bilirubin (μmol/L) | 15.5 (10.5–21.3) | 12.5 (9.1–20.6) | 19.0 (13.2–22.7) | 0.1311 |
| Aspartate aminotransferase (U/L) | 27 (22.0–39.5) (n = 44) | 32.4 (24.8–60.1) (n = 20) | 23.1 (20.3–32.8) (n = 24) | 0.0261 |
| Alanine aminotransferase (U/L) | 29.0 (20.1–50.0) | 27.3 (17.6–46.8) | 30.0 (19.7–56.0) | 0.5831 |
| Albumin (g/L) | 31.6 (30.2–34.5) | 31.0 (30.0–34.5) | 33.0 (30.3–35.4) | 0.7472 |
| Lactate (mmol/L) | 1.9 (1.5–2.3) (n = 40) | 2.1 (1.7–2.7) (n = 20) | 1.5 (1.3–2.1) (n = 20) | 0.0145 |
| Procalcitonin (ng/mL) | 0.1 (0.1–0.3) | 0.4 (0.1–2.9) | 0.1 (0.1–0.1) | <0.001 |
| Potassium (mmol/L) | 3.9 ± 0.7 | 4.2 ± 0.8 | 3.7 ± 0.5 | 0.0196 |
| Sodium (mmol/L) | 137.2 ± 4.0 | 138.2 ± 5.0 | 136.3 ± 2.8 | 0.1081 |
All the values were taken at the ICU admission.