. 2020 Nov;375(2):385–396. doi: 10.1124/jpet.120.000191

TABLE 1.

Physiologic parameters of tissues in 294-g male rats

Tissue	Volume (V, ml)	Blood Flow (Q, ml/h)
Lung	0.96^a	5548.6^b
Brain	1.41^a	123.1^b
Brain capillary	0.02^a	123.1^b
Heart	0.87^a	285^b
Intestine	8.14^b	1047.7^b
Spleen	0.43^a	336.8^b
Kidney	1.81^a	687.1^b
Muscle	127.52^b	1743.1^b
Liver	9.94^a	1424.4^c
Liver artery	NA	39.8 ^b
Skin	52.17^b	376.2^b
Bone	21.61^b	115.7^b
Bone ISF	4.02^b	115.7^b
Fat	34.44^b	422.8^b
Fat ISF	5.85^b	422.8^b
Arterial blood	5.76^b	5548.6^b
Venous blood	11.52^b	5548.6^b
Remainder	17.08^c	371.2^c

NA, not applicable.

^{^a}

Tissue vascular-corrected volume ( Inline graphic ) calculated based on experiment value using eq. 4.

^{^b}

Calculated based on the value from Shah and Betts (2012).

^{^c}

Calculated value assuming 1) 1 ng/ml tissue density, volume for remainder compartment = body weight – summation of volume for all measured tissues; 2) blood flow for remainder compartment = cardiac output – summation of blood flow for all measured tissues; 3) liver blood flow = summation of blood flow of liver artery, spleen, and intestine).