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. 2020 Oct 19;11:585351. doi: 10.3389/fgene.2020.585351

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Copyright © 2020 Zhu, Chen, Si, Li, Chen and Zhao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Scatter plot of CESD-10 scores over age by gender, genotypes, and groups of alcohol use (N = 476). CESD-10 scores over age were plotted by different combinations of ALDH2 rs671 (horizontal) and ADH1B rs1229984 (vertical) genotypes (with the number of effect alleles in parenthesis). Each dot represents a single subject. The solid and dashed black horizontal lines denote for cut-off scores of 12 (optimal) and 10 for the depression, respectively. Different genders (female/male) and groups of alcohol use (never drinkers/former drinkers/moderate drinkers/heavy drinkers) were represented by distinct shapes and colors, respectively.