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. 2020 Oct 19;11:575492. doi: 10.3389/fimmu.2020.575492

Table 3.

20 publications found in addition to those of Table 2, using broader PubMed search terms ( Supplementary Figure 1 ). Only those found relevant to the present chronic GvHD review have been listed.

Publication Gene Population Genome Graft N Variation Allele/genotypea Statistic 95% CI P
Norden et al. (28) GR EUR D MRD 458 pairs rs6198, rs33388, rs33389 non-ACT OR 0.374 0.16–0.85 0.025
Kielsen et al. (29) IL-7Rα EUR D MRD, MUD, URD 460 donors rs6897932 T HR 2.0 1.1–3.6 0.025
Takahashi et al. (30) NLRP3 Japanese D MUD 677 pairs rs10925027 T x HLA-C MM SHR 2.02 1.30–3.13 0.002
Inamoto et al. (31) BANK1 US D MRD, MUD, MMRD, MMUD 847 recipients, 808 donors rs10516487 TT HR 0.43 0.21–0.87 0.02
CD247 D rs2056626 GG or GT HR 1.23 1.00–1.51 0.04
CD247 R rs2056626 GG or GT HR 1.24 1.01–1.52 0.04
HLA-DPA1 D rs987870 CC or CT HR 2.50 1.22–5.11 0.01
HLA-DPA1 R rs987870 CC or CT HR 2.13 1.00–4.54 0.05
Resende et al. (32) IL17A Brazilian R MRD, MUD, MMUD 34 pairs rs2275913 AA NA NA 0.03b
Guillem et al. (33) TYMP EUR D MRD 448 pairs rs112723255 GG HR 1.7 1.00–2.70 0.039
Shamim et al. (34) IL-7Rα Caucasian D URD 590 pairs rs14944558 TT NA NA 0.002c
D rs1494555 GG NA NA 0.004c
Clark et al. (35) BAFF European-American R MRD, MUD 156 recipients, 153 donors rs16972217 A OR 2.72 1.38–5.39 0.004
R rs7993590 T OR 2.35 1.22–4.55 0.011
R rs12428930 C OR 2.53 1.27–5.04 0.008
R rs2893321 G OR 2.48 1.25–4.92 0.009
Takami et al. (36) FCGR3A Japanese R MUD 99 pairs rs396991 T HR 0.45 0.20–0.99 0.049
Sellami et al. (37) CTLA4 Tunisian D MRD 112 pairs rs231775 G OR 2.58 1.05–6.32 0.032c
Inamoto et al. (38) CCR9 Japanese D MRD 167 donors rs12721497 AG HR 4.1 1.1–15 0.036
Kornblit et al. (39) HMGB1 EUR D MRD, MMRD, MUD, MMUD 275 recipients, 274 donors rs2249825 G HR 1.53 1.15–2.05 0.004d
HMGB1 D rs3742305 C HR 1.57 1.18–2.09 0.002d
HMGB1 D rs41376448 insT HR 1.57 1.17–2.12 0.003d
Boukouaci et al. (40) MICA EUR R MRD 211 pairs rs1051792 GG HR 1.61 1.08–2.40 0.019
Bertinetto et al. (41) TNFA EUR R MRD 77 pairs rs361525 GG NA NA 0.027c
Laguila Visentainer et al. (42) IL6 Brazilian R MRD 118 pairs rs1800795 CC RR 3.87 1.01–14.86 0.049
IL6 D rs1800795 CC RR 6.64 2.26–19.54 <0.001
Bogunia-Kubik et al. (43) IFNγ EUR R RD, URD 160 recipients Microsatellite (CA) 3/3 genotype OR 3.18 1.22–8.27 0.018
Stark et al. (44) TNFR2 EUR D MRD  104 pairs rs1061622 GG OR 11 NA 0.024
Cullup et al. (45) IL1α EUR D MRD 98 patients, 94 donors rs1800587 T 0R 4.364 NA 0.032e
IL1α D Intron 6 VNTR Allele 2 OR 6.832 NA 0.008
IL6 R rs1800795 GG OR 5.603 NA 0.016
Cavet et al. (46) IL6 EUR R MRD 80 pairs rs1800795 GG OR 4.25 1.49–12.16 0.007
Takahashi et al. (47) IL10 Japanese Df MRD + URD 54 recipients –1,064 microsatellite, CA repeats Allele ≥13 OR 4.5 1.3–16.1 0.020

CI, confidence interval; D, donor; EUR, European; HR, hazard ratio; MMRD, mismatched related donor; MMUD, mismatched unrelated donor; MRD, matched related donor, MUD, matched unrelated donor; NA, not available; OR, odds ratio; R, recipient, RD, related donor; RR, risk ratio; SHR, subdistribution hazard ratio; URD, unrelated donor; US, United States; VNTR, variable number tandem repeat.

aThe effective allele or genotype.

bChi-square test, frequencies only.

cUnivariate analysis, not significant in multivariate analysis.

dResults significant only in the myeloablative cohort, non-significant in the nonmyeloablative cohort.

eNot significant if donor VNTR is also included.

f“Donor-derived”, DNA samples are from recipients after the transplantation.