TABLE 3.
BMI, psychometric and endocrine parameters in the course of treatment according to the changes of anxiety in women.
| Before treatment | After treatment | % change | p | |
| No change of anxiety (± 1 point, n = 20) | ||||
| GAD-7 score | 6.85 ± 6.14 | 6.65 ± 6.12 | −2.92 | 0.918 |
| PHQ-9 score | 8.56 ± 6.97 | 7.75 ± 7.03 | −9.46 | 0.725 |
| PSQ-20 score | 50.8 ± 24.7 | 47.3 ± 22.5 | −6.69 | 0.634 |
| - Worries | 47.7 ± 26.4 | 39.7 ± 29.9 | −16.8 | 0.371 |
| - Tension | 52.7 ± 28.2 | 49.0 ± 26.9 | −7.02 | 0.676 |
| - Joy | 47.0 ± 29.2 | 45.0 ± 23.9 | −4.26 | 0.814 |
| - Demands | 50.0 ± 24.4 | 45.3 ± 22.8 | −9.4 | 0.536 |
| NPY (ng/ml) | 1.11 ± 0.53 | 0.98 ± 0.45 | −11.7 | 0.41 |
| BMI (kg/m2) | 48.7 ± 8.57 | 47.8 ± 8.33 | −1.85 | 0.744 |
| Improvement of anxiety (≥ 5 points, n = 25) | ||||
| GAD-7 score | 13.4 ± 4.46 | 5.88 ± 3.72 | −56 | <0.001 |
| PHQ-9 score | 13.4 ± 5.01 | 8.65 ± 4.99 | −35.5 | 0.002 |
| PSQ-20 score | 68.1 ± 19.2 | 52.3 ± 18.6 | −23.1 | 0.005 |
| - Worries | 72.8 ± 25.1 | 50.9 ± 19.8 | −30 | 0.001 |
| - Tension | 73.9 ± 21.1 | 53.6 ± 24.7 | −27.4 | 0.003 |
| - Joy | 30.4 ± 24.4 | 37.1 ± 20.3 | + 21.9 | 0.299 |
| - Demands | 56.0 ± 26.7 | 41.9 ± 23.5 | −25.3 | 0.052 |
| NPY (ng/ml) | 1.15 ± 0.44 | 1.04 ± 0.35 | −9.79 | 0.32 |
| BMI (kg/m2) | 49.5 ± 9.51 | 48.5 ± 8.99 | −2.12 | 0.691 |
It is to note that three patients showed a worsening of their anxiety (≥ 5 points); however, the n of this group was too small in order to perform meaningful comparisons; therefore these data are not shown in this table. Statistical analysis: Data are expressed as mean ± standard deviation. Differences between two measurements were assessed using the t-test. Significant differences are displayed in bold. BMI, body mass index; GAD-7, Generalized Anxiety Disorder questionnaire; NPY, neuropeptide Y; PHQ-9, Patient Health Questionnaire; PSQ-20, Perceived Stress Questionnaire.