Table 3.
Results of multivariate analysis for overall survival by Cox regression model.
| Variable | RR | 95%CI | P |
|---|---|---|---|
| Age (≥70years vs <70years) | 1.581 | 1.137–2.199 | 0.006 |
| KPS1 (≥90/70–80/<70) | 1.845 | 1.565–2.175 | <0.001 |
| Extracranial metastases (Yes vs No) | 1.519 | 1.229–1.879 | <0.001 |
| LNS (N positive vs N negative) | 1.702 | 1.340–2.162 | <0.001 |
| Treatment modality (TKIs2 vs Conventional therapy3) | 0.374 | 0.297–0.472 | <0.001 |
1KPS, Karnofsky performance status; 2TKIs therapy: first generation of tyrosine kinase inhibitors (TKIs), gefitinib and erlotinib; 3Conventional therapy, symptomatic or systemic treatment.