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. 2020 Oct 28;12:10651–10667. doi: 10.2147/CMAR.S259077

Figure 8.

Figure 8

Mechanistic investigations indicate exosome-encapsulated miR-21 released from ESCC cells downregulates the SPRY1 expression and promotes HUVEC proliferation and angiogenesis via VEGF elevation, thereby exacerbating ESCC.