Figure 5.
The effect of GO/Cu nanocomposite-modified dressings on infected wound healing.
Notes: (A) Representative real-time photographs obtained from the CTRL, C/H, C/H/GO and C/H/GO/Cu groups at days 1, 3, 7, 10 and 14 postoperatively. (B) Variation of wound area proportion compared to the initial proportion from day 1 to 14. (C) Quantification of wound closure at day 14 after healing. *Represents a significant difference compared with the other groups at corresponding time points (p<0.01). **Represents a significant difference compared with the CTRL and C/H groups at corresponding time points (p<0.01). ***Represents a significant difference compared with the other groups at day 14 (p<0.01). #Represents a significant difference compared with the CTRL group at day 14 (p<0.05). ##Represents a significant difference compared with the CTRL and C/H groups at day 14 (p<0.05).
Abbreviations: CTRL, blank control; C/H, chitosan/hyaluronic acid dressing; C/H/GO, GO-incorporated chitosan/hyaluronic acid dressing; C/H/GO/Cu, GO/Cu-decorated chitosan/hyaluronic acid dressing; GO/Cu, graphene oxide/copper nanocomposite.