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. 2020 Oct 28;14:4579–4591. doi: 10.2147/DDDT.S258024

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© 2020 Fang et al.

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Effect of tsRNA-10277-loaded BMSC Exos on osteogenic differentiation of steroid-induced BMSCs. (A) Real time-qPCR showing the expression level of tsRNA-10277 in tsRNA-10277-loaded BMSC Exos (tsRNA-10277 Exos) and NC-loaded BMSC Exos (NC Exos). Data shown represents mean ± SD (n=3). **p<0.01 is shown for tsRNA-10277 Exos group vs NC Exos group. (B) Oil red O staining showed that the presence of tsRNA-10277 Exos led to significant decrease in lipid droplets in the SONFH model compared to that in the presence of NC Exos (Scale bars: 100um). (C) ALP staining revealed higher numbers of BMSCs stained blue/purple in tsRNA-10277 Exos group than that in the NC Exos group (Scale bars: 50um).