Table 1.
Serum Oxidative and Anti-Oxidative Biomarkers in OA Rat (Mean±S.D., n=8)
| Group | Sham | OA | OA + SAMC 2 mM |
OA + SAMC 5 mM |
|---|---|---|---|---|
| T-AOC (U/mg prot) | 3.43±0.29 | 1.07±0.22* | 1.94±0.31* | 2.85±0.45,*, # |
| SOD (U/mg prot) | 47.42±11.26 | 24.04±12.27* | 36.40±9.43* | 42.19±7.53*, # |
| CAT (U/mg prot) | 27.54±9.33 | 22.30±10.38* | 23.71±11.05* | 25.38±12.67* |
| GSH-Px (U/mg prot) | 38.40±12.33 | 16.21±10.38* | 26.75±10.05 | 33.74±12.05* |
| GSH (U/mg prot) | 7.97±1.58 | 4.08±1.21* | 5.57±1.99* | 6.78±1.37*, # |
| GSSG (U/mg prot) | 3.08±0.74 | 6.05±0.57* | 4.40±0.74* | 3.26±0.98*, # |
| Ratio of GSSG/GSH | 0.39±0.47 | 1.48±0.47* | 0.79±0.37* | 0.48±0.72*, # |
| MDA (nmol/mg prot) | 4.77±0.25 | 6.05±0.78* | 5.58±0.13* | 5.01±0.27*, # |
Notes: *P<0.05, vs sham group; #P<0.05, vs OA group.
Abbreviations: T-AOC, total antioxidant capacity; SOD, superoxide dismutase; CAT, catalase; GSH-Px, glutathione peroxidase; GSH, glutathione; GSSG, oxidized glutathione; MDA, malondialdehyde.