Table 3.

Positive predictive values for developing an aggressive MS according to the baseline number of T2 and contrast-enhancing lesions.

T2 baseline lesions	CEL	PPV (95% CI)
Unknown	Unknown	4.7% (2.1%, 7.7%)
⩾10	Unknown	8.0% (7.2%, 8.9%)
⩾10	⩾1	12.7% (8.6%, 16.9%)
⩾10	⩾2	16.3% (10.2%, 22.7%)
⩾10	⩾5	18.2% (4.8%, 33.3%)
⩾10	⩾10	36.4% (12.5%, 66.7%)
⩾20	Unknown	11.5% (8.6%, 13.9%)
⩾20	⩾1	15.8% (9.8%, 22.4%)
⩾20	⩾2	18.9% (10.6%, 28.1%)
⩾20	⩾5	22.2% (6.3%, 41.7%)
⩾20	⩾10	40.0% (14.3%, 71.4%)

MS: multiple sclerosis; CEL: contrast-enhancing lesions; PPV: positive predictive value; 95% CI: 95% confidence interval.