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. 2019 Nov 1;26(13):1719–1728. doi: 10.1177/1352458519881759

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© The Author(s), 2019

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 3. — MRI outcomes in early relapsers through 6 years. (a) Proportions free of MRI disease activity and (b) median percentage yearly change in BPF over 6 years in patients with relapse between alemtuzumab Courses 1 and 2 in the core CARE-MS I and CARE-MS II studies. Freedom from MRI disease activity was defined as the absence of new gadolinium-enhancing T1 and new/enlarging T2 hyperintense lesions.

BPF: brain parenchymal fraction; CARE-MS: Comparison of Alemtuzumab and Rebif^® Efficacy in Multiple Sclerosis; CIs: confidence intervals; MRI: magnetic resonance imaging.

Error bars denote 95% CIs.