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. 2019 Nov 4;26(13):1691–1699. doi: 10.1177/1352458519885613

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© The Author(s), 2019

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 3. — ORs for reaching an EDSS score of 6.0. (a) After 8 years of follow-up. (b) After 15 years of follow-up. For the purpose of illustration, the range of NfL assessments was broken down into tertiles; n indicates the total for each category. Hypothesis testing of the association of NfL levels with cumulative incidence of progression to EDSS score ⩾6.0 was conducted using Fisher’s exact test, as well as Wald chi-square test based on Firth’s penalized univariate logistic regression. OR are shown relative to the lowest tertile.

EDSS: Expanded Disability Status Scale; NfL: neurofilament light chain; NS: not significant; OR: odds ratio.