Outcomes of advanced stage chronic lymphocytic leukemia (CLL) cases according to subset classification. (A) Median time-to-first-treatment (TTFT) for the subset #1: 20.6 months, subset #2: 28.5 months, subset #4: 42.8 months, subset #8: 5.5 months, U-CLL: 17.8 months, M-CLL: 36.1 months. (B) Median timeto- next-treatment (TTNT) for the subset #1: 60.2 months, subset #2: 57.3 months, subset #4: not reached, subset #8: 43.7 months, U-CLL: 47.4 months, M-CLL: not reached. (C) Median progression-free survival (PFS) for subset #1: 41.7 months, subset #2: 33.3 months, subset #4: not reached, subset #8: 26.3 months, U-CLL: 26.5 months, M-CLL: 54.7 months. (D) Median overall survival (OS) for subset #1: 67.5 months, subset #2: not reached, subset #4: not reached, subset #8: 43.3 months, U-CLL: 78.9 months, M-CLL: not reached; Cum: cumulative.