Table 2.
Cumulative dose of oliceridine and conventional opioids.
| Cumulative dosing | Oliceridine cohort | CO cohort∗ | |
|---|---|---|---|
| All patients | N | 213 | 225 |
| Dose, mg, mean (SD) | 51.4 (38.1) | 112.1 (99.4) | |
| Dose, mg, median | 42.5 | 79.2 | |
|
| |||
| Patients experiencing respiratory depression | n (%) | 17 (8.0) | 69 (30.7) |
| Dose, mg, mean (SD) | 40.7 (26.6) | 96.5 (69.0) | |
| Dose, mg, median | 35 | 74 | |
∗∗Cumulative dosage for morphine + hydromorphone + hydrocodone + meperidine + oxycodone + tramadol in MME (patients may have one or more of these treatments).