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. 2020 Feb 13;105(11):2667–2670. doi: 10.3324/haematol.2019.235556

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Copyright© 2020 Ferrata Storti Foundation

This article is distributed under the terms of the Creative Commons Attribution Noncommercial License (by-nc 4.0) which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.

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Figure 1. — Event-free survival (EFS), progression-free survival (PFS) and overall survival (OS) of patients stratified according to Myc and BCL-2 expression. (A-C) The double expressor (DE) subgroup had a significant inferior clinical course, while the double negative (DN) subset had a superior outcome and the MYC-/BCL- 2+ subset had an intermediate prognosis, with the differences being statistically significant for EFS, PFS and OS. (D-F) The cases were stratified according to MYC protein expression only, patients with MYC >70% experienced inferior outcome in EFS (P=0.005), PFS (P=0.004) and OS (P=0.002) in comparison to patients with low MYC expression (<40%). No difference in prognosis was seen between patients whose tumors had MYC expression <40% and 40-70%.