Table 2.

Univariate and multivariate analyses for trends in the proportion of opioid use disorder-related emergency department visits

	Ref	Crude PR	95% CI	P value	Adjusted PR	95% CI	P value
Gender
Female	Ref	1			1
Male		1.59	(1.54 to 1.65)	<0.001	1.4	(1.36 to 1.44)	<0.001
Unidentified		0.89	(0.64 to 1.25)	0.524	0.7	(0.50 to 0.97)	0.032
Age (years) (reference)
0–9	5	0.17	(0.16 to 0.18)	<0.001	0.17	(0.17 to 0.18)	<0.001
10–19	15	0.71	(0.70 to 0.72)	<0.001	0.72	(0.71 to 0.72)	<0.001
20–29	25	1.24	(1.23 to 1.25)	<0.001	1.23	(1.22 to 1.24)	<0.001
30–39	35	1.48	(1.45 to 1.50)	<0.001	1.45	(1.42 to 1.47)	<0.001
40–49	45	1.39	(1.36 to 1.43)	<0.001	1.35	(1.33 to 1.38)	<0.001
50–59	55	1.12	(1.09 to 1.16)	<0.001	1.08	(1.06 to 1.11)	<0.001
60–69	65	0.8	(0.78 to 0.83)	<0.001	0.75	(0.75 to 0.80)	<0.001
70+	90	0.24	(0.23 to 0.26)	<0.001	0.23	(0.22 to 0.24)	<0.001
Year (quantitative)		0.981	(0.974 to 0.987)	<0.001	0.979	(0.973 to 0.985)	<0.001
ICD10 code
[F11] Mental and behavioural disorders due to use of opioids		9.52	(9.17 to 9.89)	<0.001	8.96	(8.64 to 9.28)	<0.001
[T40] Poisoning by narcotics and psychodysleptics		0.09	(0.07 to 0.10)	<0.001	0.08	(0.07 to 0.10)	<0.001
[T400] Opium		0.08	(0.07 to 0.09)	<0.001	0.08	(0.07 to 0.09)	<0.001
[T401] Heroin		0.14	(0.13 to 0.15)	<0.001	0.13	(0.13 to 0.14)	<0.001
[T402] Other opioids	Ref	1			1
[T403] Methadone		0.1	(0.10 to 0.11)	<0.001	0.1	(0.10 to 0.11)	<0.001
[T404] Other narcotics		0.14	(0.13 to 0.16)	<0.001	0.14	(0.13 to 0.16)	<0.001
[T406] Unspecified narcotics		1.65	(1.57 to 1.73)	<0.001	1.66	(1.58 to 1.73)	<0.001

ICD10, International Classification of Diseases, version 10; PR, proportion ratios.