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. 2020 Oct 29;12:1758835920968725. doi: 10.1177/1758835920968725

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© The Author(s), 2020

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 3. — Pain assessment (Brief Pain Inventory; BPI) during abiraterone treatment in symptomatic patients.

Data for mean pain intensity were available from 119 symptomatic patients at baseline, 71 at 6-month follow-up, 43 at 12-month follow-up, 29 at 18-month follow-up and 12 at 24-month follow-up. Corresponding numbers for worst pain intensity: 125, 74, 44, 30 and 12; interference of pain: 108, 71, 39, 29, 11. The signed rank test was used to test changes from baseline in the three BPI domains. Tests were not performed at 18 and 24 months of follow-up due to the limited number of patients with available information at those time points at the present interim analysis. p-values were <0.001 at 6 months and 0.101 at 12 months for the mean pain intensity domain; <0.001 at 6 months and 0.001 at 12 months for the worst pain intensity domain; and 0.004 at 6 months and 0.008 at 12 months for the interference of pain domain.

*p < 0.05.