Table 1.
Clinical characteristics of the patients.
| Characteristics | All patients(n=30) | Pregnancy-negativegroup(n=23) | Pregnancy-positivegroup(n=7) | Intergroup difference |
|---|---|---|---|---|
| Age, years | 34.7 ± 4.6 | 35.8 ± 4.1 | 31.0 ± 4.5 | 0.019 |
| Nulligravid, n (%) | 18 (60) | 14 (60.9) | 4 (57.1) | 0.141 |
| Nulliparous, n (%) | 24 (80) | 20 (87.0) | 4 (57.1) | 0.334 |
| Duration of infertility, years | 4.2 ± 2.1 | 21.0 ± 13.2 | 17.6 ± 16.9 | 0.266 |
| Body mass index, kg/m2 | 23.9 ± 4.3 | 23.7 ± 4.6 | 24.4 ± 3.3 | 0.532 |
| Cause of infertility, n (%) | ||||
| Poor semen quality | 7 (23.3) | 5 (21.7) | 2 (28.6) | 0.974 |
| Tubal factor | 5 (16.7) | 3 (13.0) | 2 (28.6) | |
| Endometriosis | 4 ( 13.3 ) | 3 (13.0) | 1 (14.3) | |
| Other female factor | 3 (10.0) | 3 (13.0) | 0 | |
| Combined male-female factor | 4 (13.3) | 4 (17.4) | 0 | |
| Unexplained | 7 (23.3) | 5 (21.7) | 2 (28.6) | |
| No. of stimulation procedures initiated previously, n (%) | ||||
| Cycle 0 | 11 (36.7) | 7 (30.4) | 4 (57.1) | 0.127 |
| Cycle 1 | 9 (30.0) | 6 (26.1) | 3 (42.9) | |
| Cycle 2 | 7 (23.3) | 7 (30.4) | 0 | |
| Cycle 3 | 3 (10.0) | 3 (13.0) | 0 | |
| Cycle 4 | 0 | 0 | 0 | |
| Serum estradiol, pmol/L | 1402.3 ± 950.3 | 1319.3 ± 1011.9 | 1706.7 ± 659.4 | 0.236 |
| Total dose of gonadotropin, IU | 2106.4 ± 976.1 | 0.8 ± 0.2 | 0.8 ± 0.2 | 0.532 |
| Duration of stimulation, days | 10.9 ± 2.6 | 14.1 ± 1.1 | 13.6 ± 1.0 | 0.266 |
| No. of retrieved oocytes | 5.2 ± 3.23 | 4.8 ± 2.5 | 6.6 ± 5.0 | 0.598 |
| No. of matured oocytes (metaphasis II) | 4.2 ± 2.7 | 3.8 ± 2.2 | 5.7 ± 4.0 | 0.311 |
| No. of Grade 1 embryos | 2.7 ± 1.4 | 2.4 ± 1.2 | 3.6 ± 1.9 | 0.174 |
| No. of transferred embryos (fresh only) | 1.9 ± 0.7 | 1.8 ± 0.8 | 2.0 ± 0.6 | 0.666 |
| hCG on day 12, IU | 279.0 ± 654.5 | 11.8 ± 28.9 | 1118.9 ± 954.7 | <0.001 |
| No. of chemical pregnancies, n (%) | 8 (26.6) | 1 | 7 | |
| No. of clinical pregnancies, n (%) | 7 (23.3) | 0 | 7 | |
Numbers in bold indicate significance. hCG=human chorionic gonadotropin.