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. 2020 Nov 2;146(5):e20200464. doi: 10.1542/peds.2020-0464

TABLE 4.

Multilevel Models of Infant Mortality by Rural-Urban Classification of Resident County, 2014–2016

Urban-Rural Classification Model 1a Model 2a Model 3a Model 4a Model 5b
OR 95% CI P OR 95% CI P OR 95% CI P OR 95% CI P OR 95% CI P
Total infant deaths
 Metropolitan
  Large metropolitan central 1.12 1.05–1.21 **** 1.10 1.02–1.18 *** 1.09 1.02–1.16 *** 1.02 0.97–1.07 NS 1.00 0.95–1.05 NS
  Large metropolitan fringe 1.00 1.00 1.00 1.00 1.00
  Medium metropolitan 1.17 1.11–1.24 **** 1.16 1.10–1.22 **** 1.09 1.04–1.14 **** 1.09 1.04–1.13 **** 1.06 1.02–1.10 ***
  Small metropolitan 1.20 1.13–1.27 **** 1.19 1.12–1.26 **** 1.08 1.02–1.13 *** 1.06 1.02–1.11 *** 1.06 1.01–1.11 *
 Rural
  Micropolitan 1.23 1.16–1.30 **** 1.22 1.15–1.29 **** 1.04 0.99–1.10 NS 1.04 0.99–1.09 NS 1.01 0.97–1.06 NS
  Noncore (most rural) 1.28 1.20–1.36 **** 1.26 1.18–1.34 **** 1.04 0.98–1.10 NS 1.03 0.97–1.08 NS 1.00 0.95–1.06 NS
 Health care
  HPSA 1.01 0.97–1.05 NS 1.03 1.00–1.07 NS
  FQHC/RHC 0.99 0.95–1.03 NS 1.03 0.99–1.06 NS
  Obstetric hospital 1.05 1.02–1.09 *** 1.00 0.97–1.02 NS
  NICU 1.09 1.04–1.14 **** 1.04 0.99–1.08 NS
 Advantage index 0.84 0.83–0.86 **** 0.82 0.81–0.84 ****
BIC statistic 798 137.5 798 174.7 797 933.6 797 658.6 618 383.2
Neonatal deaths
 Metropolitan
  Large metropolitan central 1.14 1.05–1.22 **** 1.10 1.02–1.18 ** 1.10 1.03–1.18 *** 1.01 0.96–1.07 NS 0.98 0.91–1.05 NS
  Large metropolitan fringe 1.00 1.00 1.00 1.00 1.00
  Medium metropolitan 1.17 1.10–1.24 **** 1.15 1.09–1.22 **** 1.10 1.04–1.16 **** 1.10 1.04–1.15 **** 1.08 1.03–1.14 ***
  Small metropolitan 1.14 1.07–1.21 **** 1.13 1.06–1.20 **** 1.04 0.99–1.11 NS 1.04 0.98–1.10 NS 1.04 0.98–1.11 NS
 Rural
  Micropolitan 1.17 1.10–1.24 **** 1.17 1.10–1.25 **** 1.03 0.97–1.09 NS 1.04 0.98–1.10 NS 1.03 0.96–1.09 NS
  Noncore (most rural) 1.17 1.10–1.26 **** 1.18 1.10–1.26 **** 1.00 0.94–1.07 NS 1.02 0.96–1.09 NS 1.00 0.93–1.08 NS
 Health care
  HPSA 1.03 0.99–1.08 NS 1.05 1.00–1.09 *
  FQHC/RHC 1.01 0.97–1.06 NS 1.03 0.98–1.07 NS
  OB hospital 1.05 1.02–1.10 *** 1.00 0.97–1.04 NS
  NICU 1.07 1.01–1.13 ** 1.03 0.98–1.08 NS
 Advantage index 0.88 0.86–0.90 **** 0.87 0.85–0.89 ****
BIC statistic 551 437.2 551 481.2 551 359.5 551 284.8 415 463.5
Postneonatal Deaths
 Metropolitan
  Large metropolitan central 1.13 1.02–1.24 ** 1.13 1.02–1.25 ** 1.07 0.99–1.17 NS 1.03 0.96–1.10 NS 1.03 0.97–1.09 NS
  Large metropolitan fringe 1.00 1.00 1.00 1.00 1.00
  Medium metropolitan 1.20 1.11–1.30 **** 1.19 1.10–1.29 **** 1.08 1.01–1.16 * 1.08 1.01–1.14 ** 1.02 0.97–1.08 NS
  Small metropolitan 1.35 1.22–1.48 **** 1.34 1.22–1.47 **** 1.15 1.06–1.24 **** 1.12 1.04–1.20 *** 1.08 1.02–1.15 *
 Rural
  Micropolitan 1.36 1.24–1.49 **** 1.34 1.22–1.47 **** 1.07 0.99–1.16 NS 1.05 0.98–1.12 NS 1.00 0.93–1.07 NS
  Noncore (most rural) 1.48 1.33–1.65 **** 1.41 1.27–1.58 **** 1.10 1.01–1.21 * 1.03 0.95–1.12 NS 1.01 0.93–1.09 NS
 Health care
  HPSA 0.97 0.92–1.03 NS 1.01 0.96–1.07 NS
  FQHC/RHC 0.96 0.91–1.01 NS 1.03 0.98–1.08 NS
  OB hospital 1.06 1.01–1.11 ** 1.00 0.96–1.04 NS
  NICU 1.12 1.04–1.20 *** 1.04 0.98–1.11 NS
 Advantage index 0.78 0.76–0.80 *** 0.75 0.73–0.77 ***
BIC statistic 330 663.3 330 705.9 330 467.8 330 266.9 266 771.3

Model 1 = NCHS category plus county centroids and regional controls. Model 2 = model 1 plus county-level health care factors (HPSA, obstetric hospital, NICU, FQHC/RHC). Model 3 = model 1 plus county-level socioeconomic status (advantage index). Model 4 (full structural model) = model 1+ county-level socioeconomic status (advantage index) plus county population characteristics (fraction white, Black, Hispanic, other; TFR). Model 5 (complete model) = model 4 plus individual-level variables. NS, not significant; —, not applicable.

*

P < .05.

**

P < .01.

***

P < .005.

****

P < .001.

a All models control for county centroid.

b This model excludes Connecticut, Rhode Island, New Jersey, Georgia, Virginia, and Hiawaii and includes all individual level covariates.