Figure 2.
a) A graphic representation of all binary interactions between the peptides studied in this work. The scale indicates the maximum percent deviation from a weighted average of individual activities predicted if no synergy were present. *indicates mixing with peptide 1, ** with 2. (b-e) Hydrolytic activity of fibrils as a function of mixture compositions for b) 7 and 3 c) 6 and 1 d) 7 and 1 e) 4 and 1. Experimental conditions: 25 mM Tris, pH 8.0, 25 μM total peptide, 0.1 mM Zn2+, 195 μM pNPA.