Figure 5.
a) The dependence of catalytic efficiency in pNPA hydrolysis on the composition of the fibrils made by mixing 7 and 7D. Experimental conditions: 25 mM Tris, pH 8.0, 25 μM total peptide, 0.1 mM Zn2+, 195 μM pNPA. b) ThT fluorescence of the fibrils formed by mixing 7D with 7 as a function of fibril composition.