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. Author manuscript; available in PMC: 2020 Nov 2.
Published in final edited form as: Neuroimage. 2020 Jul 5;220:117129. doi: 10.1016/j.neuroimage.2020.117129

Fig. 4.

Fig. 4.

Left fusiform cortical thickness trajectories before harmonization (left), after longitudinal ComBat REML (center), and after longitudinal ComBat MSR (right). Individual subject trajectories and linear mixed effects model fit for the fixed effects are shown for the different diagnostic groups. Scanner was included as a fixed effect covariate for unharmonized data. Fitted lines are for females at the mean baseline age of 75.3 years. Estimated coefficients (coef) for late mild cognitive impairment (LMCI) by time interaction and Alzheimer’s disease (AD) by time interaction, and Kenward-Roger (KR) test p-values, are displayed in lower right corners.