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. 2020 Oct 28;15:8331–8343. doi: 10.2147/IJN.S263956

Figure 3.

Figure 3

COMSOL simulation and fabrication of the Exo-Load microfluidic device. (A, B) The numerical study of fluid-velocity distribution and the streamline flow analysis in the microchannel of Exo-Load, showing overall consistency in the streamlined laminar flow of the fluid through the microfluidic channel. (C, D) The numerical study of drug-concentration distribution in the microchannel, demonstrating that DOX, saponin, and exosomes were mixed in the microchannel during perfusion. (E, F) Representative image of the Exo-Load microfluidic device: Design 1 = linear type, Design 2 = sigmoid type (Scale bar: 10 mm).