Table 3.
GO Process* Wild-Type Chronic Hypoxia versus Chronic Hypoxia HIF-2α KO Right Ventricle (Log Fold Change >1.5)
| GO Term | Description | P Value | FDR q Value | Enrichment |
|---|---|---|---|---|
| GO:0030595 | Leukocyte chemotaxis | 4.84 × 10−5 | 6.85 × 10−1 | 12.47 |
| GO:1901700 | Response to oxygen-containing compound | 1.63 × 10−4 | 1.00 × 1 | 3.19 |
| GO:0050900 | Leukocyte migration | 3.23 × 10−4 | 1.00 × 1 | 8.35 |
| GO:0060326 | Cell chemotaxis | 3.64 × 10−4 | 1.00 × 1 | 8.14 |
| GO:0097529 | Myeloid leukocyte migration | 3.79 × 10−4 | 1.00 × 1 | 11.64 |
| GO:0031349 | Positive regulation of defense response | 5.60 × 10−4 | 1.00 × 1 | 5.82 |
| GO:0006954 | Inflammatory response | 7.25 × 10−4 | 1.00 × 1 | 5.54 |
| GO:0033993 | Response to lipid | 7.45 × 10−4 | 1.00 × 1 | 4.05 |
| GO:0006952 | Defense response | 7.81 × 10−4 | 1.00 × 1 | 3.31 |
| GO:0050727 | Regulation of inflammatory response | 8.21 × 10−4 | 1.00 × 1 | 5.41 |
| GO:0050729 | Positive regulation of inflammatory response | 9.88 × 10−4 | 1.00 × 1 | 9.04 |
*No pathways were significantly altered for GO function.