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. Author manuscript; available in PMC: 2020 Nov 2.
Published in final edited form as: Neurobiol Aging. 2020 Apr 20;93:25–34. doi: 10.1016/j.neurobiolaging.2020.04.013

Table 4.

Post hoc structural measurements

Structural measurements Mean (SD)
F (significance)
ε4 non-carriers
ε4 carriers
 
Males (n = 10) Females (n = 11) Males (n = 9) Females (n = 9) ε4 status Sex ε4 × sex
Left caudate (mm3) 3493.60 (439.56) 3531.55 (620.92) 4170.78 (666.75) 3616.56 (486.29) 3.47 (p > 0.05) 2.02 (p > 0.05) 2.10 (p > 0.05)
Right caudate (mm3) 3492.30 (415.74) 3628.82 (960.68) 4219.78 (387.79) 3704.22 (541.19) 1.91 (p > 0.05) 0.58 (p > 0.05) 2.05 (p > 0.05)
Left putamen (mm3) 4679.30 (824.49) 4658.55 (607.08) 5502.22 (741.86) 4930.44 (620.86) 5.52a (p = 0.03) 0.96 (p > 0.05) 2.61 (p > 0.05)
Right putamen (mm3) 4424.10 (670.16) 4401.27 (668.75) 5419.67 (625.01) 4889.22 (628.16) 11.96a (p = 0.002) 1.22 (p > 0.05) 2.27 (p > 0.05)
Left parahippocampal gyrus (mm) 2.39 (0.34) 2.52 (0.35) 2.01 (0.38) 2.62 (0.44) 1.54 (p > 0.05) 9.65a (p = 0.004) 2.95 (p > 0.05)
Right parahippocampal gyrus (mm) 2.32 (0.24) 2.40 (0.36) 2.36 (0.38) 2.44 (0.16) 0.36 (p > 0.05) 0.77 (p > 0.05) 0.04 (p > 0.05)
Left isthmus cingulate gyrus (mm) 2.67 (0.21) 2.51 (0.23) 2.36 (0.15) 2.47 (0.17) 3.10a (p = 0.09) 0.57 (p > 0.05) 4.54a (p = 0.041)
Right isthmus cingulate gyrus (mm) 2.68 (0.24) 2.47 (0.35) 2.46 (0.24) 2.46 (0.19) 1.12 (p > 0.05) 0.90 (p > 0.05) 0.78 (p > 0.05)

MANCOVA controlled for age and ICV.

Key: ICV, intracranial volume; SD, standard deviation.

a

Denotes significance.