Table 2.

Outcomes and Renin Concentration

	Patients below the Study Population Median Renin [Median (IQR)]		P Value	Patients above the Study Population Median Renin [Median (IQR)]		P Value
	Treatment with Placebo (n = 63)	Treatment with Angiotensin II (n = 64)		Treatment with Placebo (n = 73)	Treatment with Angiotensin II (n = 55)
28-d mortality, %	44 (33–58)	45 (34–58)	0.70	70 (59–80)	51 (39–65)	0.01
Ventilator liberation by Day 7 (alive and vent-free), %	38 (27–52)	27 (18–40)	0.20	14 (8–25)	28 (18–43)	0.07
RRT liberation by Day 7 (alive and RRT free), %	14 (4–46)	28 (13–54)	0.33	12 (5–27)	43 (25–66)	0.01
ICU discharge by Day 28, %	52 (41–65)	39 (28–52)	0.13	22 (14–33)	44 (32–58)	0.02

Definition of abbreviations: IQR = interquartile range; RRT = renal replacement therapy.