Table 3. Tetranucleotide frequency analysis.

	Molecule	CR			NR
		Mean	sd	p-value	Mean	sd	p-value
HL-46	EI34DRAFT_6181	0.2323	0.1883	0.154	0.1518	0.1429	0.983
HL-46	EI34DRAFT_7210	0.2042	0.0696	0.896	0.1701	0.1332	0.975
HL-48	CY41DRAFT	0.0276	0.0577	0.387	0.4425	0.2689	<0.001a
HL-49	K302DRAFT	0.0522	0.0431	0.757	0.2340	0.2164	<0.001
HL-53	Ga0003345	0.0261	0.0451	0.001	0.3851	0.1525	<0.001
HL-55	K417DRAFT	0.0458	0.0726	0.086	0.2774	0.2168	0.004
HL-58	CD01DRAFT	0.0761	0.1451	0.008	0.2974	0.969	0.004
HL-91	Ga0058931_11	0.0266	0.0213	0.313	0.3043	0.1416	0.011
HL-91	Ga0058931_12	ndb	nd	nd	nd	nd	nd
HL-91	Ga0058931_13	nd	nd	nd	nd	nd	nd
HL-91	Ga0058931_14	0.0557	0.0647	0.004	0.3614	0.2052	<0.001
HL-93	Ga0071314_11	0.0925	0.0738	0.993	0.2254	0.1595	0.062
HL-109	Ga0071312_11	0.0262	0.0401	0.396	0.3148	0.1842	0.087
HL-109	Ga0071312_12	0.0216	0.0281	0.076	0.2907	0.1913	0.231
HL-109	Ga0071312_13	0.0048	0.0019	0.538	0.3651	0.2299	0.016
HL-111	Ga0071316_11	0.0396	0.0561	0.322	0.4504	0.1640	<0.001

Notes:

^aBold text indicates significant result.

^bNot determined because the entire molecule was missing from the reconstructed genome.