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. 2020 Apr 30;11(5):583–590. doi: 10.1039/c9md00537d

Table 3. Metabolism stabilities of D1 and D2 a .

Compd. % inh. at 10 μM 1A2/2C9/2D6/3A4 t 1/2 (min)
Human Rat
D1 42/63/40/38 23 17
D2 12/84/61/43 37 15

aData were the means of three experiments with errors within 30% of the mean.