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. Author manuscript; available in PMC: 2020 Nov 2.
Published in final edited form as: Cell Rep. 2020 Oct 13;33(2):108239. doi: 10.1016/j.celrep.2020.108239

Figure 3. Dietary Supplementation of BCAA Does Not Impede Sustained Weight Loss and Improved Glucose Tolerance after VSG.

Figure 3.

(A) Body weight (% change) following VSG and sham surgery.

(B–D) Total plasma amino acid levels (B), total BCAA (C), and percent BCAA levels (relative to total amino acid levels) (D) in plasma after overnight fast.

(E and F) Fat mass (E) and lean mass (F) after VSG and sham surgery.

(G) Average daily food intake after VSG and sham surgery.

(H) ipGTT (2 g/kg) was performed 12 weeks after VSG and sham surgery. Shown as blood glucose response and AUC.

(I) HOMA2 IR, calculated based on fasting blood glucose and insulin levels, 17 weeks after surgery. Animals, n = 6–8/group. Data are shown as means ± SEM. *p < 0.05 (two-way ANOVA with Tukey’s post-test) with legends: *p < 0.05 sham HFD compared to VSG HFD; d, p < 0.05 sham HFD compared to sham HFD+BCAA; #p < 0.05 sham HFD+BCAA compared to VSG HFD+BCAA.