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. Author manuscript; available in PMC: 2021 Jan 1.
Published in final edited form as: Expert Rev Hematol. 2020 Jun 12;13(7):719–729. doi: 10.1080/17474086.2020.1772745

Table 2.

Use of regional anesthesia and hemostatic prophylaxis in women with factor XI deficiency.

Reference Number of anesthesia events Number of patients with hemostatic prophylaxis Factor XI comments
Kadir et al. [29] 2 0 Documented as mild/moderate factor XI deficiency.
Myers et al. [28] 14 0 Unclear. 14 women received regional anesthesia prior to their diagnosis of FXI deficiency, but specific factor activity was not noted.
Chi et al. [26] 14 7 Both SD patients in this manuscript received prophylaxis (rFVIIa & FXIc then TA, respectively); however, it is not clear what for of anesthesia they received. All others PD.
Chi et al. [27] 5 5 Both SD and PD patients.
Singh et al. [32] 9 5 1 SD patient, all others PD
Verghese et al. [30] 16 16 All PD (FXI ≥ 20%)
Gerber et al. [35] 24 3 SD patients received prophylaxis. No PD patients received prophylaxis.

SD, severe deficiency; PD, partial deficiency.