Appendix Table 3.

Differences of outcomes between patients with peak lactate level ≥7.25 and <7.25 (mmol/L)

	All patients (n=97), n (%)	Peak lactate ≥7.25 (n=14), n (%)	Peak lactate <7.25 (n=83), n (%)	P*
In-hospital mortality, n (ratio)	14 (14.4)	8 (57)	6 (7.2)	0.003
Length of hospital stay, median (IQR)	19 (13-29)	15 (3-35)	19 (14-27)	0.702
Length of ICU stay, median (IQR)	5 (4-7.5)	8 (3-13)	5 (4-7)	0.174
Complications
Low cardiac output	12 (12.3)	5 (35.7)	7 (8.4)	0.066
ECMO	6 (6.2)	4 (28.6)	2 (2.4)	0.058
IABP	10 (10.3)	2 (14.3)	8 (9.6)	0.601
AKI requiring dialysis	24 (24.7)	9 (64.3)	15 (18.1)	0.004
ARDS	3 (3.1)	2 (14.3)	1 (1.2)	0.203
Rebleeding	9 (9.3)	4 (28.6)	5 (6.0)	0.100
Liver failure, n (ratio)	8 (8.2)	3 (21.4)	5 (6.0)	0.208

*Comparison between patients with peak lactate level ≥ 7.25 and < 7.25 mmol/L. ECMO: Extracorporeal membrane oxygenation, IABP: Intra-aortic balloon pump, AKI: Acute kidney injury, ARDS: Acute respiratory distress syndrome, IQR: Interquartile ranges, ICU: Intensive care unit