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. 2020 Oct 25;11(12):2526–2533. doi: 10.1021/acsmedchemlett.0c00521

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© 2020 American Chemical Society

This article is made available via the ACS COVID-19 subset for unrestricted RESEARCH re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.

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IC₅₀ plots and values for the top five compounds active against SARS-CoV-2 M^pro from in vitro FRET-based assay. IC₅₀ plots were generated from averaged kinetic data in triplicate for (A) manidipine, (B) boceprevir, (C) lercanidipine, (D) efonidipine, and (E) bedaquiline.