Table 3.
Numbers and percentages of women per 10-year risk category.
| 10-year risk category based on BOADICEA | |||||
|---|---|---|---|---|---|
| Total | Including age and PRS | Including age, risk factors, and PRS | |||
| <2.5% | >2.5% | <2.5% | >2.5% | ||
| Unaffected women | |||||
| All | 4214 | 1481 (35%) | 2733 (65%) | 2359 (56%) | 1855 (44%) |
| Incident BC cases | |||||
| All | 163 | 33 (20%) | 130 (80%) | 62 (38%) | 101 (62%) |
| Invasive BC | |||||
| All | 142 | 30 (21%) | 112 (79%) | 52 (37%) | 90 (63%) |
| Grade 1 | 19 | 2 (11%) | 17 (89%) | 3 (16%) | 16 (84%) |
| Grade 2 | 38 | 7 (18%) | 31 (82%) | 12 (32%) | 26 (68%) |
| Grade 3 | 43 | 13 (30%) | 30 (70%) | 21 (49%) | 22 (51%) |
| Unknown | 42 | 8 (19%) | 34 (81%) | 16 (38%) | 26 (62%) |
| In situ BC | |||||
| All | 21 | 3 (14%) | 18 (86%) | 10 (48%) | 11 (52%) |
| Grade 1 | 3 | 2 (67%) | 1 (33%) | 2 (67%) | 1 (33%) |
| Grade 2 | 3 | 1 (33%) | 2 (67%) | 2 (67%) | 1 (33%) |
| Grade 3 | 13 | 0 (0%) | 13 (100%) | 5 (38%) | 8 (62%) |
| Unknown | 2 | 0 (0%) | 2 (100%) | 1 (50%) | 1 (50%) |
BC breast cancer, BOADICEA Breast and Ovarian Analysis of Disease Incidence and Carrier Estimation Algorithm, PRS polygenic risk score.