Table 1.
Chance parameter | Probability | Values for sensitivity analysis | Reference(s) |
---|---|---|---|
Operative mortality | 0.047 | 0.023–0.071 | [21–23] |
COVID-19 mortality | 0.25 | 0.150–0.520 | [4, 31, 33, 34] |
Immediate resection | |||
COVID-19 infection | 0.014 | 0.0001–0.100 | * |
Stage 1 | 0.93 | 0.817–0.895 | [24, 25] |
Stage 2 | 0.06 | 0.107–0.143 | [24, 25] |
Stage 3 | 0.01 | 0.005–0.034 | [24, 25] |
Delayed resection | |||
COVID-19 infection | 0.00001 | 0.01 | * |
Surgery | 0.994 | 0.95–1.0 | [24] |
Stage 1 | 0.91 | 0.789–0.895 | [26–29] |
Stage 2 | 0.07 | 0.111–0.200 | [26–29] |
Stage 3 | 0.02 | 0.005–0.038 | [26–29] |
No surgery (disease progression) | 0.006 | 0–0.05 | [24] |
*Parameters set by research team based on base case clinical scenario, current local data