Simulation snapshots depicting the structural changes in aggregation of
nine strands of WT and acetylated (K16Ac, K28Ac, and KKAc)
Aβ42 peptides in aqueous solution. For each
structure, the predicted hydrophobic patches (yellow) were mapped on the
molecular surface (violet) using SPDB software. (A) WT, (B) K16Ac, (C) K28Ac,
and (D) KKAc aggregates. The water molecules are not shown for clarity.