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[Preprint]. 2020 Nov 2:2020.10.27.20220863. [Version 3] doi: 10.1101/2020.10.27.20220863

Figure 1. HLA alleles associated with higher risk of hospitalization in a COVID-19 positive patient cohort.

Figure 1.

COVID-19 positive patients were split into two groups per allele tested, depending on whether they were predicted to have the HLA allele under scrutiny or not. We ran the Kaplan-Meier estimator (R package survival) using the Overmyer et al. cohort [20] HFD-45 metric for estimating the remission probability of patients without or with alleles (a) A*11:01, (b) C*04:01 or (c) DQA1*01:02 and mechanical ventilator-free days to estimate the statistical significance of the more severe disease outcome observed in COVID-19 patients with (d) C*04:01. Log-rank p values were calculated for each (R package survminer) and are indicated on the plots.