Table 2.
ORs for the risk for synovial sarcoma according to race/ethnicity, birth weight and birth order, and parental age, California 1978–2015.
| Entire population (n = 244 cases and 12,200 controls) |
non-Hispanic White only (n = 93 cases 1,939 controls) |
Hispanic only (n = 112 cases 2,345 controls) |
||||
|---|---|---|---|---|---|---|
| Case n (%) |
Control n (%) |
Unadjusted OR (95% CI) |
Adjusteda OR (95% CI) |
Adjusteda OR (95% CI) |
Adjusteda OR (95% CI) |
|
| Sex | ||||||
| Female | 106(43.3) | 5,940 (48.7) | 1.00 (Reference) | 1.00 (Reference) | 1.00 (Reference) | 1.00 (Reference) |
| Male | 138 (56.6) | 6,260 (51.3) | 1.24 (0.96–1.60) | 1.21 (0.94–1.57) | 1.44 (0.93–2.24) | 0.96 (0.65–1.43) |
| Race/ethnicity | ||||||
| White | 93 (38.1) | 4,834 (39.6) | 1.00 (Reference) | 1.00 (Reference) | ||
| Black | 17 (7.0) | 1,097 (9.0) | 0.81 (0.48–1.36) | 0.90 (0.53–1.54) | ||
| Hispanic | 112 (45.9) | 4,965 (40.7) | 1.17 (0.89–1.55) | 1.48 (1.06–2.08) | ||
| Asian | 20 (8.2) | 1,139 (9.3) | 0.91 (0.56–1.49) | 1.03 (0.60–1.78) | ||
| Other | 2 (0.8) | 165 (1.4) | 0.63 (0.15–2.58) | 0.67 (0.16–2.78) | ||
| Birth weight (grams) | ||||||
| 250–2,499 | 15 (6.1) | 721 (5.9) | 0.98 (0.57–1.70) | 1.06 (0.57–1.98) | 0.94 (0.29–3.12) | 0.78 (0.27–2.23) |
| 2,500–2,999 | 32 (13.1) | 1,928 (15.8) | 0.78 (0.52–1.17) | 0.78 (0.52–1.18) | 0.71 (0.34–1.48) | 0.80 (0.43–1.52) |
| 3,000–3,499 | 95 (38.9) | 4,480 (36.7) | 1.00 (Reference) | 1.00 (Reference) | 1.00 (Reference) | 1.00 (Reference) |
| 3,500–3,999 | 71 (29.1) | 3,674 (30.1) | 0.91 (0.67–1.24) | 0.90 (0.66–1.23) | 0.70 (0.42–1.19) | 1.15 (0.72–1.82) |
| 4,000+ | 31 (12.7) | 1,397 (11.5) | 1.05 (0.69–1.58) | 1.09 (0.72–1.66) | 1.00 (0.52–1.90) | 1.26 (0.65–2.47) |
| Every 500 g | 1.08 (0.95–1.23) | 1.07 (0.87–1.33) | 1.22 (1.00–1.48) | |||
| Birth order | ||||||
| 1st | 128 (52.5) | 4,873 (39.9) | 1.00 (Reference) | 1.00 (Reference) | 1.00 (Reference) | 1.00 (Reference) |
| 2nd | 66 (27.0) | 3,932 (32.2) | 0.64 (0.47–0.86) | 0.61 (0.44–0.84) | 0.58 (0.35–0.98) | 0.54 (0.32–0.89) |
| 3rd and higher | 50 (20.5) | 3,395 (27.8) | 0.56 (0.40–0.78) | 0.53 (0.36–0.77) | 0.46 (0.23–0.90) | 0.53 (0.30–0.95) |
| Maternal age (years) | ||||||
| <20 | 30 (12.3) | 1,484 (12.2) | 1.21 (0.78–1.88) | 0.92 (0.53–1.59) | 0.79 (0.24–2.63) | 0.97 (0.46–2.07) |
| 20–24 | 76 (31.1) | 3,373 (27.6) | 1.35 (0.96–1.90) | 1.13 (0.78–1.66) | 1.16 (0.59–2.30) | 1.23 (0.70–2.16) |
| 25–29 | 60 (24.6) | 3,591 (29.4) | 1.00 (Reference) | 1.00 (Reference) | 1.00 (Reference) | 1.00 (Reference) |
| 30–34 | 56 (23.0) | 2,532 (20.8) | 1.32 (0.92–1.91) | 1.49 (1.00–2.23) | 2.61 (1.39–4.88) | 0.68 (0.31–1.50) |
| ≥35 | 22 (9.0) | 1,220 (10.0) | 1.08 (0.66–1.77) | 1.06 (0.59–1.91) | 1.08 (0.41–2.88) | 1.81 (0.77–4.30) |
| Paternal age (years) | ||||||
| <25 | 66 (27.0) | 2,938 (24.1) | 1.55 (1.05–2.29) | 1.41 (0.86–2.32) | 1.35 (0.56–3.25) | 1.72 (0.82–3.62) |
| 25–29 | 78 (32.0) | 3,421 (28.0) | 1.57 (1.08–2.30) | 1.60 (1.06–2.41) | 1.87 (0.97–3.60) | 1.59 (0.80–3.16) |
| 30–34 | 42 (17.2) | 2,901 (23.8) | 1.00 (Reference) | 1.00 (Reference) | 1.00 (Reference) | 1.00 (Reference) |
| 35–39 | 31 (12.7) | 1,484 (12.2) | 1.44 (0.90–2.30) | 1.49 (0.92–2.41) | 1.60 (0.80–3.20) | 2.07 (0.87–4.90) |
| ≥40 | 22 (9.0) | 865 (7.1) | 1.76 (1.04–2.96) | 1.90 (1.07–3.35) | 2.39 (1.05–5.44) | 1.32 (0.45–3.90) |
| Unknown | 5 (2.0) | 591 (4.8) | 0.58 (0.23–1.48) | 0.63 (0.24–1.64) | 0.54 (0.12–2.50) | |
a
The adjusted ORs were derived from multivariable logistic regression models in which all the variables listed in the table were included simultaneously. Three separate models were fit for the overall study population, Hispanics, and non-Hispanic Whites, respectively.