. 2020 Oct 29;13:4085–4094. doi: 10.2147/DMSO.S279475

Table 2.

Antihyperglycemic Activity of Repeated Daily Doses of the Crude Extract in Diabetic Mice

Fasting Blood Glucose Level (mg/dl)				% Reduction
Group	Baseline	7th day	14th day	7th day	14th day
DC	320.33±10.25	324.83±8.26	327.17±5.67	−1.40	−2.13
GLC 5 mg/kg	343.83±16.52^n***	167.50±10.23^{a*,β,n**}	141.00±20.21^{a*,β,n**}	51.28	58.99
CE 100 mg/kg	297.50±10.57^n***	256.17±16.25^a,β,n**	228.45±13.26^{a,β,n***}	13.89	23.21
CE 200 mg/kg	313.93±18.24^n***	233.33±13.24^{a,β,n**}	194.00±10.54^{a*,β,n**}	25.67	38.20
CE 400 mg/kg	311.67±13.25^n***	205.53±11.25^{a*,β,n**}	176.00±15.24^{a*,β,n**}	34.06	43.53
NC	91.34±9.54^a***	89.98±10.23^a***	90.78±11.36^a***	1.49	0.61

Notes: Each value represents mean ± SEM; n=6 for each group. ^acompared to the diabetic control, ⁿcompared to the normal control, and ^βcompared to baseline blood glucose level. ^*p<0.05, ^**p<0.01, and ^***p<0.001.

Abbreviations: CE, H. abyssinica crude extract; GLC, glibenclamide; DC, diabetic control; NC, normal control.