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. 2020 Oct 29;12:10875–10886. doi: 10.2147/CMAR.S271365

Table 2.

The Result of UVA and MVA Cox Proportional Hazards Regression

Variables Univariable Multivariable
HR (95% CI) P HR (95% CI) P
Age 1.02 (0.99~1.05) 0.109 1.02 (0.99~1.04) 0.055
Sex <0.001 0.092
 Female Reference Reference
 Male 2.71 (1.62~4.56) 1.71 (0.92~3.19)
Smoking <0.001 0.147
 Yes 2.73 (1.70~4.38) 1.55 (0.86~2.78)
 No Reference Reference
Family history 0.471
 Yes 1.45 (0.53~3.98)
 No Reference
Pathology 0.002 0.728
 Squamous cell carcinoma Reference Reference
 Adenocarcinoma 2.50 (1.46~4.32) 1.04 (0.49~1.80)
 Others 1.82 (0.78~4.27) 1.69 (0.44~3.21)
T stage <0.001 <0.001
 T1 Reference Reference
 T2 1.43 (0.86~2.38) 1.07 (0.64~1.8)
 T3 2.64 (1.16~6.04) 1.08 (0.54~3.06)
 T4 16.8(5.11~55.48) 10.11(2.93~34.89)
Adjuvant therapy 0.002 0.038
 Yes 2.14 (1.34~3.44) 1.69 (1.03~2.76)
 No Reference Reference
Volume <0.001 <0.001
 <200mm^3 Reference Reference
 200~600mm^3 2.44 (1.22~4.89) 1.98 (1.06~3.99)
 >600mm^3 4.32 (2.52~7.38) 3.13 (1.75~5.62)