Table 3.
Baseline and 10-Years Follow-Up Clinical and Lung Function Characteristics of the COPD Patients Included in the Validation Study
| Variable | Baseline | 10 Years Follow-Up | p-value |
|---|---|---|---|
| BMI* | 27±6 | 27±6 | 0.928 |
| Active smoking (%) | 45 | 45 | 0.998 |
| FEV1 (L)* | 1.62±0.52 | 1.40±0.51 | 0.006 |
| FEV1 (% pred)* | 64±19 | 61±18 | 0.318 |
| FVC (% pred)* | 100±21 | 97±22 | 0.396 |
| FEV1/FVC (% pred)* | 52±11 | 50±11 | 0.253 |
| PaO2* | 75±10 | 69±12 | 0.002 |
| DLco* | 81±23 | 63±23 | <0.001 |
| IC/TLC (%)* | 37±9 | 34±9 | 0.113 |
| 6MWD (mts)* | 529±88 | 458±124 | 0.003 |
| mMRC dysnea** | 1 (0–1) | 1 (0–2) | 0.165 |
| BODE index** | 1 (0–2) | 1 (0–2) | 0.707 |
Notes: *Data are presented as mean ±SD. **Data are presented as median (25th–75thpc). Bold values denote statistical significance at the p < 0.05 level.
Abbreviations: BMI, body mass index; DLCO, diffusion capacity for carbon monoxide; FEV1, forced expiratory volume in one second; FVC, forced vital capacity; IC/TLC, inspiratory capacity to total lung capacity ratio; PaO2, partial oxygen tension; % pred, per cent predicted; 6MWD, six minutes walking distance test.