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. 2020 Nov 2;17(11):e1003407. doi: 10.1371/journal.pmed.1003407

Table 2. Estimated health gains, costs, and cost-effectiveness of eliminating industrial TFA from the Australian food supply over 10 years and over the population lifetime.

10 years Estimate (95% UI) Lifetime Estimate (95% UI)
IHD events avoided 9,931 (8,429; 11,532) 56,759 (44,493; 69,358)
IHD deaths avoided 2,294 (1,765; 2,851) 41,877 (32,855; 51,138)
Life years gained 5,532 (4,285; 6,845) 127,268 (106,176; 148,917)
HALYs gained 6,377 (5,151; 7,685) 108,321 (91,187; 125,986)
Change in IHD-related healthcare costs, million AUD 80 (-98; -69) -538 (-628; -463)
    Per capita, AUD -15.0 (-18.3; -11.9) -21.7 (-26.0; -17.3)
Change in total healthcare costs, million AUD -14 (-34; 3) 157 (48; 260)
    Per capita, AUD -19.7 (-24.5; -15.2) -23.0 (-28.8; -17.5)
Policy costs, million AUD 21.5 (21.3; 21.6) 56.0 (55.9; 56.2)
    Governmental costs 14.3 (14.2; 14.5) 47.6 (47.4; 47.7)
    Legislation 1.1 (0.9; 1.2) 1.1 (0.9; 1.2)
    Monitoring 13.3 46.5
    Industry costs 6.6 7.8
    Initial reformulation 6.0 6.0
    Annual industry costs 0.5 1.8
    Repackaging 0.6 0.6
Net costs1, million AUD 7.2 (-12.9; 24.4) 212.9 (104.1; 315.8)
ICER2, AUD/HALY 1,153 (dominant; 3,578) 1,961 (1,015; 2,756)

AUD, Australian dollar; HALY, health-adjusted life year; ICER, incremental cost-effectiveness ratio; IHD, ischemic heart disease; TFA, trans-fatty acid; UI, uncertainty interval.

1Calculated as the sum of policy costs and change in total healthcare costs.

2Calculated as net costs divided by HALYs gained.